京都大学大学院農学研究科 応用生命科学専攻

生物調節化学研究室

業績リスト

Original Articles

Abdel-Wahab M, Miyashita M. Ota Y, Juichi H, Okabe R, Moustafa S, Fouda M, Abdel-Rahman M, Saber S, Nakagawa Y.
Isolation, structural identification and biological characterization of two conopeptides from the Conus pennaceus venom. Biosci. Biotechnol. Biochem., in press

Ito-Harashima S, Matsuura M, Kawanishi M, Nakagawa Y, Yagi T.
New reporter gene assays for detecting natural and synthetic molting hormone agonists using yeasts expressing ecdysone receptors of various insects. FEBS Open Bio, in press

Sugiura A, Horoiwa S, Aoki T, Takimoto S, Yamagami A, Nakano T, Nakagawa Y, Miyagawa H.
Discovery of a nonsteroidal brassinolide-like compound, NSBR1. J. Pesic. Sci., in press.

Watanabe B, Yamamoto S, Yokoi T, Sugiura A, Horoiwa S, Aoki T, Miyagawa H, Nakagawa Y.
Brassinolide-like activity of castasterone analogs with varied side chains against rice lamina inclination. Bioorg. Med. Chem., , in press.

Review Articles

中川好秋
脱皮ホルモン様活性化合物のQSAR
日本農薬学会誌 第42巻 第1号 38-43 (2017)

宮川 恒
農薬はどう教えられているか
日本農薬学会誌 第42巻 第1号 153-158 (2017)

Original Articles

Kitanaka A, MIyashita M, Kubo A, Satoh T, Toyoda M, Miyagawa H.
N-Terminal Derivatization with Structures Having High Proton Affinity for Discrimination between Leu and Ile Residues in Peptides by High-Energy Collision-Induced Dissociation.Mass Spectrom. (Tokyo), 5, A0051 (2016).

Miyata K, Nakagawa Y, Kimura Y, Ueda K, Akamatsu M.
Structure-activity relationships of dibenzoylhydrazines for the inhibition of P-glycoprotein-mediated quinidine transport.Biorg. Med. Chem., 24, 3184-3191 (2016).

Takimoto S, Sugiura A, Minami S, Tasaka T, Nakagawa Y, Miyagawa H.
In silico exploration for agonists/antagonists of brassinolide.Biorg. Med. Chem. Lett., 26, 1709-1714 (2016)

Kim Y, Miyashita M, Miyagawa H.
Early signaling events induced by the peptide elicitor PIP-1 necessary for acetosyringone accumulation in tobacco cells.Biosci. Biotechnol. Biochem., 80, 1054-1057 (2016).

Miyata K, Nakagawa Y, Kimura Y, Ueda K, Akamatsu M.
In vitro and in vivo evaluations of the P-glycoprotein-mediated efflux of dibenzoylhydrazines.Tox. Appll. Pharm., 298, 40-47 (2016).

Abdel-Wahab M, Miyashita M, Kitanaka A, Juichi H, Sarhan M, Fouda M, Abdel-Rahman M, Saber S, Nakagawa Y.
Characterization of the venom of the vermivorous cone snail Conus fulgetrum. Biosci. Biotechnol. Biochem. 80, 1879-1882 (2016).

Aoki H, Ishihara A, Miyashuta M, Miyagawa H, Yatou O, Saito K.
Involvement of the Rice OsSAUR51 gene in the auxin-related field resistance mechanism against bacterial blight disease. JARQ-JAPAN AGRICULTURAL RESEARCH QUARTERLY, 50,219-227 (2016).

Ishihara A, Fukami A, Matsuda Y, Nakajima H, Miyagawa H.
Accumulation of indole-3-acetic acid in rice s1 mutant leaves infected with Bipolaris oryzae. J. Phytopathology , 164,509-519 (2016).

Review Articles

Nakagawa Y, Sonobe H.
Ecdysteroids. In "Handbook of Hormones-Comparative endocrinology for basic and clinical research”, http://booksite.elsevier (Eds. Takei Y, Ando H, Tsutsui K), The Japan Society for Comparative Endocrinology, e98-1-e98-14, 557-559 (2016)

Nakagawa Y, Sonobe H.
20-Hydroxyecdysone. In "Handbook of Hormones-Comparative endocrinology for basic and clinical research”, http://booksite.elsevier (Eds. Takei Y, Ando H, Tsutsui K), The Japan Society for Comparative Endocrinology, e98A-2, 560-563 (2016)

Unsworth JB, Corsi C, Van Emon JM, Farenhorst A, Hamilton DJ, Howard CJ, Hunter R, Jenkins JJ, Kleter GA, Kookana RS, Lalah JO, Leggett M, Miglioranza KSB, Miyagawa H, Peranginangin N, Rubin B, Saha B, Shakil NA
Developing global leaders for research, regulation, and stewardship of crop protection chemistry in the 21st century. J. Agric. Food Chem. , 64,52-60 (2016).

Original Articles

Bunta Watanabe, Saki Minami, Hideaki Ishida, Ryuzo Yoshioka, Yoshiaki Nakagawa, Tsuyoshi Morita, Ken’ichiro Hayashi.
Stereospecific inhibitory effects of CCG-1423 on the cellular events mediated by myocardin-related transcription factor A.PLoS One., 2015 Aug 21;10(8):e0136242. doi: 10.1371/journal.pone.0136242.

Nagao J, Miyashita M, Nakagawa Y, Miyagawa H.
Chemical synthesis of La1 isolated from the venom of the scorpion Liocheles australasiae and determination of its disulfide bonding pattern. J. Pept. Sci., 21, 636-643 (2015)

Kim Y, Miyashita M, Miyagawa H.
Photocontrol of Elicitor Activity of PIP-1 to Investigate Temporal Factors Involved in Phytoalexin Biosynthesis. J. Agric. Food Chem., 63 5894-5901 (2015)

Yokoi T, Minami S, Nakagawa Y, Miyagawa H.
Structure-activity relationship of imidazothiadiazole analogs for the binding to the ecdysone receptor of insect cells. Pest. Biochem. Physiol., 120, 40-50 (2015)

Review Articles

Original Articles

Kim Y, Komoda E, Miyashita M, Miyagawa H.
Continuous stimulation of the plant immune system by the peptide elicitor PIP-1 is required for phytoalexin biosynthesis in tobacco cells. J. Agric. Food Chem., 62, 5781-5788 (2014)

Ozaki S, Nakagawa Y, Shirai O, Kano K.
Substituent effect on the thermodynamic solubility of structural analogs: Relative contribution of crystal packing and hydration. J. Pharm. Sci., 103, 3524-3531 (2014)

Kamachi S, Nagao J, Miyashita M, Nakagawa Y, Miyagawa H, Tada T.
Crystallization and preliminary X-ray diffraction studies of La1 from Liocheles australasiae. Acta Cryst., F70, 915-917 (2014)

Morishita C, Minakuchi C, Yokoi T, Takimoto S, Hosoda A, Akamatsu M, Tamura H, Nakagawa Y.
cDNA cloning of ecdysone receptor (EcR) and ultraspiracle (USP) from Harmonia axyridis and Epilachna vigintioctopunctata and the evaluation of the binding affinity of ecdysone agonists to the in vitro translated EcR/USP heterodimer. J. Pestic. Sci., 39, 76-84 (2014)

Hayashi K, Watanabe B, Nakagawa Y, Minami S, Morita T.
RPEL proteins are the molecular targets for CCG-1423, an inhibitor of Rho signaling. PLoS One., 2014 Feb 18;9(2):e89016. doi: 10.1371/journal.pone.0089016.

Kitamura S, Harada T, Hiramatsu H, Shimizu R, Miyagawa H, Nakagawa Y.
Structural requirement and stereospecificity of tetrahydroquinolines as potent ecdysone agonists. Bioorg. Med. Chem. Lett., 24, 1715-1718 (2014)

Review Articles

Nishioka T, Kasama T, Kinumi T, Makabe H, Matsuda F, Miura D, Miyashita M, Nakamura T, Tanaka K, Yamamoto A.
Winners of CASMI2013: Automated Tools and Challenge Data. Mass Spectrometry, 3, S0039-S (2014)

Sabljic A, Nakagawa Y.
Biodegradation and quantitative structure-activity relationship (QSAR). In “Non-First Order Degradation and Time-Dependent Sorption of Organic Chemicals in Soil” (W. Chen, A. Sabljic, S. A. Cryer, R. S. Kookana, Eds.), ACS Symp. Ser. 1174. American Chemical Society, Washington, D.C., pp. 57-84 (2014).

Sabljic A, Nakagawa Y.
Sorption and quantitative structure-activity relationship (QSAR). In “Non-First Order Degradation and Time-Dependent Sorption of Organic Chemicals in Soil” (W. Chen, A. Sabljic, S. A. Cryer, R. S. Kookana, Eds.), ACS Symp. Ser. 1174. American Chemical Society, Washington, D.C., pp. 85-118 (2014).

中川好秋
実験技術講座 QSAR編 第4回 農薬科学におけるQSARの活用.
日本農薬学会誌39巻18-31 (2014)

Original Articles

Ishimaru K, Hirotsu N, Madoka Y, Murakami N, Hara N, Onodera H, Kashiwagi T, Ujiie K, Shimizu B, Onishi A, Miyagawa H, Katoh E.
Loss of function of the IAA-glucose hydrolase geneTGW6 enhances rice grain weight and increases yield Nature Genetics, 45, 707-711 (2013)

Kanaoka S, Kimura Y, Fujikawa M, Nakagawa Y, Ueda K, Akamatsu M.
Substrate recognition by P-glycoprotein efflux transporters: Structure-ATPase activity relationship of diverse chemicals and agrochemicals. J. Pestic. Sci., 38, 112-122 (2013)

Kawachi T, Miyashita M, Nakagawa Y, Miyagawa H.
Isolation and characterization of an anti-insect β-toxin from the venom of the scorpion Isometrus maculatus. Biosci. Biotechnol. Biochem., 77, 205-207 (2013)

Morou E, Emmanouel L, Pavlidi N, Zotti M, Iatrou K, Nakagawa Y, Smagghe G, Vontas J, Swevers L.
A New Dibenzoylhydrazine with Insecticidal Activity against Anopheles Mosquito Larvae. Pest Manag. Sci., 69, 827-833 (2013)

Nihashi Y, Miyashita M, Awane H, Miyagawa H.
Differential 14N/15N-Labeling of Peptides Using N-Terminal Charge Derivatization with a High-Proton Affinity for Straightforward de novo Peptide Sequencing, Mass Spectometry, 2, A0024(2013); DOI:10.5702/massspectrometry.A0024

その他

宮川 恒
農学RI年頭雑感
RI ニュース No.57, 2-4 (2013)

宮川 恒
農薬の必要性
農業および園芸 第8巻(第1号) 1-2 (2013)

Original Articles

Ichiki Y, Kawachi T, Miyashita M, Nakagawa Y, Miyagawa H.
Isolation and characterization of a novel non-selective β-toxin from the venom of the scorpion Isometrus maculatus. Biosci. Biotechnol. Biochem., 76, 2089-2092 (2012)

Ogura T, Nakagawa Y, Swevers L, Smagghe G, Miyagawa H.
Quantitative evaluation of the molting hormone activity in coleopteran cells established from the Colorado potato beetle, Leptinotarsa decemlineata. Pestic. Biochem. Physiol., 104, 1-8 (2012)

Review Articles

Nakagawa Y, Harada T.
Advanced Screening to Identify Novel Pesticides. In “Advanced Technologies for Managing Insect Pests” (Ishaaya I, Palli RS, Horowitz R, Eds.), Springer, Dordrecht, pp. 135-163, 2012

Dinan L, Nakagawa Y, and Hormann RE.
Structure-activity relationships of ecdysteroids and non-steroidal ecdysone agonists. Adv. Insect Physiol., 43, 251-298 (2012)

Original Articles

Miyashita M, Matsushita K, Nakamura S, Akahane S, Nakagawa Y, Miyagawa H.
LC/MS/MS identification of 20-hydroxyecdysone in a scorpion (Liocheles australasiae) and its binding affinity to in vitro-translated molting hormone receptors. Insect Biochem. Mol. Biol., 41, 932-937 (2011)

Horita S, Matsushita N, Kawachi T, Ayabe R, Miyashita M, Miyakawa T, Nakagawa Y, Nagata K, Miyagawa H, Tanokura M.
Solution structure of a short-chain insecticidal toxin LaIT1 from the venom of scorpion Liocheles australasiae. Biochem. Biophys. Res. Comm., 411, 738-744 (2011)

Miyashita M, Oda M, Ono Y, Komoda E, Miyagawa H.
Discovery of a Small Peptide from Combinatorial Libraries That Can Activate the Plant Immune System by a Jasmonic Acid Signaling Pathway, ChemBioChem, 12, 1323-1329 (2011)

Miyashita M, Hanai Y, Awane H, Yoshikawa T, Miyagawa H.
Improving peptide fragmentation by N-terminal derivatization with high proton affinity. Rapid Commun. Mass Spectrom. 25, 1130-40 (2011)

Harada T, Nakagawa Y, Ogura T, Yamada Y, Ohe T, Miyagawa H.
Virtual screening for ligands of the insect molting hormone receptor. J. Chem. Inf. Model, 51, 296-305 (2011)

Ishihara A, Nakao T, Yuko M, Murai M, Ichimaru N, Tanaka C, Nakajima H, Wakasa K, Miyagawa H.
Probing the role of tryptophan-derived secondary metabolism in defense responses against Bipolaris oryzae infection in rice leaves by a suicide substrate of tryptophan decarboxylase. Phytochemistry, 72, 7-13 (2011)

Review Articles

中川好秋
脱皮の分子メカニズムとその阻害剤の構造活性相関
日本農薬学会誌 36巻, 300-303 (2011)

中川好秋
エクジステロイド受容体の構造と機能  
脱皮と変態の生物学;昆虫と甲殻類のホルモン作用の謎を追う(園部治之・長澤寛道編), 東海大学出版会, pp.99-121 (2011)

中川好秋
昆虫成長制御剤概論
脱皮と変態の生物学;昆虫と甲殻類のホルモン作用の謎を追う(園部治之・長澤寛道編), 東海大学出版会, pp.147-166 (2011)

Original Articles

Seino Y, Ogura T, Tsubota T, Shimomura M, Nakakura T, Tan A, Mita K, Shinoda T, Nakagawa Y, Shiotsuki T.
Characterization of juvenile hormone epoxide hydrolase and its telated genes in larval development of silkworm, Bombyx mori. Biosci. Biotech. Biochem., 74, 1421-1429 (2010)

Ishimoto M, Rahman SM, Hanafy MS, Khalafalla MM, El-Shemy HA, Nakamoto Y, Kita Y, Takanashi K, Matsuda F, Murano Y, Funabashi T, Miyagawa H, Wakasa K.
Evaluation of amino acid content and nutritional quality of transgenic soybean seeds with high-level tryptophan accumulation. Molecular Breeding, 25, 313-326 (2010)

Matsuda F, Ishihara A, Takanashi K, Morino K, Miyazawa H, Wakasa K, Miyagawa H.
Metabolic profiling analysis of genetically modified rice seedlings that overproduce tryptophan reveals the occurrence of its inter-tissue translocation, Plant Biotechnology, 27, 17-27 (2010)

Soin T, De Geyter E, Mosallanejad H, Iga M, Martin D, Ozaki S, Kitsuda S, Harada T, Miyagawa H, Stefanou D, Kotzia G, Efrose R, Labropoulou V, Geelen D, Iatrou K, Nakagawa Y, Janssen CR, Smagghe G, Swevers L.
Assessment of species specificity of moulting accelerating compounds in Lepidoptera: comparison of activity between Bombyx mori and Spodoptera littoralis by in vitro reporter and in vivo toxicity assays. Pest Manag. Sci., 66, 526-35 (2010)

Soin T, Swevers L, Kotzia G, Iatrou K. Janssen CR, Rouge P, Harada T, Nakagawa Y, Smagghe G.
Comparison of the activity of non-steroidal ecdysone agonists between dipteran and lepidopteran insects, using cell-based EcR reporter assays. Pest Manag. Sci., 66, 1215-29 (2010)

Miyashita M, Sakai A, Matsushita N, Hanai Y, Nakagawa Y, Miyagawa H.
Novel amphipathic linear peptide with both insect toxicity and antimicrobial activity from the venom of the scorpion Isometrus maculates. Biosci. Biotech. Biochem., 74, 364-69 (2010)

Tsurushima T, Minami Y, Miyagawa H, Nakayashiki H, Tosa Y, Mayama S.
Induction of chlorosis, ROS generation and celldeath by a toxin isolated from Pyricularia oryzae. Biosci. Biotechnol. Biochem., 74, 2220-2225 (2010)

Original Articles

Harada T, Nakagawa Y, Wadkins RW, Potter PM, Wheelock CE.
Comparison of benzil and trifluoromethyl ketone (TFK)-mediated carboxyesterase inhibition using classical and 3D-quantitative structure-activity relationship analysis. Bioorg. Med. Chem., 17, 149-164 (2009)

Mizuno T, Miyashita M, Miyagawa H.
Cellular internalization of arginine-rich peptides into tobacco suspension cells: a structure-activity relationship study. J. Peptide Sci., 15, 259-263 (2009)

Matsushita N, Miyashita M, Ichiki Y, Ogura T, Sakuradani E, Nakagawa Y, Shimizu S, Miyagawa H.
Purification and cDNA Cloning of LaIT2, a Novel Insecticidal Toxin from Venom of the Scorpion Liocheles australasiae. Biosci. Biotech. Biochem., 73, 2769-2772 (2009)

Harada T, Nakagawa Y, Akamatsu M, Miyagawa H.
Evaluation of hydrogen bonds of ecdysteroids in the ligand-receptor interactions using a protein modeling system. Bioorg. Med. Chem., 17, 5868-5873 (2009)

Review Articles

Fujita T, Nakagawa Y.
SAR and QSAR Analyses of substituted dibenzoylhydrazines for their mode of Action as ecdysone agonists. Endocrine Disruption Modeling (Devillers, J., ed.), Taylor & FrancisGroup ,Boca Raton, FL, 359-379 (2009)

Nakagawa Y, Hormann RE, Smagghe G.
SAR and QSAR studies for in vivo and in vitro activities of ecdysone agonists. Ecdysones: Structures and Functions (Smagghe, G., ed.), Springer, 475-509 (2009)

中川好秋
昆虫脱皮の分子メカニズム−新たな害虫防除手法を探る. 昆虫科学が拓く未来(藤崎憲二、西田律夫、佐久間正幸編), 京都大学出版会, pp.271-298 (2009)

宮下正弘,中川好秋
日本に生息するサソリの持つ毒素の研究. 昆虫科学が拓く未来(藤崎憲二、西田律夫、佐久間正幸編)、京都大学出版会, pp.304-306 (2009)

宮川 恒
植物の防御に関わる含窒素二次代謝成分に関する研究
日本農薬学会誌34巻127-135 (2009)

Original Articles

Arai H, Watanabe B, Nakagawa Y and Miyagawa H.
Synthesis of ponasterone A derivatives with various steroid skeleton moieties and evaluation of their binding to the ecdysone receptor of Kc cells. Steroids, 73(14), 1452-1464 (2008)

Ishihara A, Hashimoto Y, Tanaka C, Dubouzet J.G., Nakao T, Matsuda F, Nishioka T, Miyagawa H and Wakasa K.
The tryptophan pathway is involved in the defense responses of rice against pathogenic infection via serotonin production. Plant J., 54(3), 481-495 (2008)

Hormann R.E., Smagghe G. and Nakagawa Y.
Multidimensional quantitative structure-activity relationships of diacylhydrazine toxicity in Spodoptera exigua, Chilo suppressalis, and Leptinotarsa decemlineata.QSAR Comb. Sci., 27 1098-1112 (2008)

Ichimaru N, Murai M, Kakutani N, Kako J, Ishihara A, Nakagawa Y, Nishioka T, Yagi T and Miyoshi H.
Synthesis and characterization of new piperazine-type inhibitors for mitochondrial NADH-ubiquinone oxidoreductase (complex I). Biochemistry, 47(40), 10816-10826 (2008)

Mosallanejad H, Soin T, Swevers L, Iatrou K, Nakagawa Y and Smagghe G.
Non-steroidal ecdysteroid agonist chromafenozide: Gene induction activity, cell proliferation inhibition and larvicidal toxicity, Pestic. Biochem. Physiol., 92, 70-76 (2008)

Morita D, Katoh K, Harada T, Nakagawa Y, Matsunaga I, Miura T, Adachi A, Igarashi T and Sugita M.
Trans-species activation of human T cells by rhesus macaque CD1b molecules. Biochem. Biophys. Res. Commun., 377(3), 889-893 (2008)

Yamada T, Matsuda F, Kasai K, Fukuoka S, Kitamura K, Tozawa Y, Miyagawa H and Wakasa K.
Mutation of a Rice Gene Encoding a Phenylalanine Biosynthetic Enzyme Results in Accumulation of Phenylalanine and Tryptophan. Plant Cell, 20(5), 1316-1329 (2008)

Ishihara A, Hashimoto Y, Miyagawa H, Wakasa K.
Induction of serotonin accumulation by feeding of rice striped stem borer in rice leaves. Plant Signaling & Behavior, 3, 714-716 (2008)

Review Articles

中川好秋、宮川恒
新しい殺虫剤、21世紀の農学第3巻−植物を守る(佐久間正幸編).京都大学学術出版会、 pp.123-150 (2008)

甲斐建次、宮川恒
植物種により異なるオーキシンの代謝経路:LC/MS/MSで明らかになった代謝の多様性、化学と生物、第46巻、 pp.152-153 (2008)

Original Articles

Dubouzet J.G., Ishihara A, Matsuda F, Miyagawa H, Iwata H and Wakasa K.
Integrated metabolomic and transcriptomic analyses of high-tryptophan rice expressing a mutant anthranilate synthase alpha subunit. J. Exp. Bot., 58(12), 3309-3321 (2007)

Ishihara A, Matsuda F, Miyagawa H and Wakasa K.
Metabolomics for metabolically manipulated plants: effects of tryptophan overproduction. Metabolomics, 3(3), 319-334 (2007)

Fujita T and Nakagawa Y.
QSAR and mode of action studies of insecticidal ecdysone agonists. SAR QSAR Environ. Res., 18, 77-88 (2007)

Heinzle E, Matsuda F, Miyagawa H, Wakasa K and Nishioka T.
Estimation of metabolic fluxes, expression levels and metabolite dynamics of a secondary metabolic pathway in potato using label pulse-feeding experiments combined with kinetic network modelling and simulation. Plant Journal, 50, 176-187 (2007)

Kai K, Horita J, Wakasa K and Miyagawa H.
Three oxidative metabolites of indole-3-acetic acid from Arabidopsis thaliana. Phytochemistry, 68(12), 1651-1663 (2007)

Kai K, Nakamura S, Wakasa K and Miyagawa H.
Facile Preparation of Deuterium-Labeled Standards of Indole-3-Acetic Acid (IAA) and Its Metabolites to Quantitatively Analyze the Disposition of Exogenous IAA in Arabidopsis thaliana. Biosci. Biotechnol. Biochem., 71(8), 1946-1954 (2007)

Kai K, Wakasa K and Miyagawa H.
Metabolism of indole-3-acetic acid in rice: Identification and characterization of N-beta-d-glucopyranosyl indole-3-acetic acid and its conjugates. Phytochemistry, 68, 2512-2522 (2007)

Matsuda F, Wakasa K and Miyagawa H.
Metabolic flux analysis in plants using dynamic labeling technique: Application to tryptophan biosynthesis in cultured rice cells. Phytochemistry, 68(16-18), 2290-2301 (2007)

Matsushita N, Miyashita M, Sakai A, Nakagawa Y and Miyagawa H.
Purification and characterization of a novel short-chain insecticidal toxin with two disulfide bridges from the venom of the scorpion Liocheles australasiae. Toxicon, 50, 861-867 (2007)

Minakuchi C, Ogura T, Miyagawa H and Nakagawa Y.
Effects of the structures of ecdysone receptor (EcR) and ultraspiracle (USP) on the ligand-binding activity of the EcR/USP heterodimer. J. Pest. Sci., 32, 379-384 (2007)

Miyagawa H and Ueyama I.
Summary of Scientific Programs in 11th IUPAC International Congress of Pesticide Chemistry. In Pesticide Chemsitry (Ohkawa, H. Miyagawa, H. and Lee, P.W., eds.), pp.459-478, Wiley-VCH (2007)

Miyashita M, Otake Y, Oda M and Miyagawa H.
Development of a high-throughput screening method using a cell-based, lawn format assay for the identification of novel plant defense activators from combinatorial peptide libraries. Journal of Agricultural and Food Chemistry, 55(3), 806-811 (2007)

Miyashita M, Otsuki J, Hanai Y, Nakagawa Y and Miyagawa H.
Characterization of peptide components in the venom of the scorpion Liocheles australasiae (Hemiscorpiidae). Toxicon, 50, 428-437 (2007)

Nakagawa Y, Sakai A, Magata F, Ogura T, Miyashita M and Miyagawa H.
Molecular cloning of the ecdysone receptor and the retinoid X receptor from the scorpion Liocheles australasiae. Febs Journal, 274, 6191-6203 (2007)

Tamaki H, Shimada A, Ito Y, Ohya M, Takase J, Miyashita M, Miyagawa H, Nozaki H, Nakayama R and Kumagai H.
LPT1 encodes a membrane-bound O-acyltransferase involved in the acylation of lysophospholipids in the yeast Saccharomyces cerevisiae. J. Biol. Chem., 282(47), 34288-34298 (2007)

Review Articles

Fujita T and Nakagawa Y.
QSAR and mode of action studies of insecticidal ecdysone agonists. SAR QSAR En Environ Res., 18, 77-88 (2007)

中川好秋
脱皮ホルモン類縁体.ホルモンハンドブック新訂eBook版(日本比較内分泌学会編).南江堂, pp.III-B-7-b (2007)

Original Articles

Miyagawa H.
Eleventh IUPAC International Congress of Pesticide Chemistry, Kobe, Japan, 2006 - From crop protection to crop production and beyond. In Pest Management Science (Vol. 62), pp.687-689 (2006)

Minakuchi C, Suzuki J, Toda K, Akamatsu M and Nakagawa Y.
Corrigendum to ''estimation of the hydrophobicity of 2,4-diphenyl-1,3-oxazoline analogs and QSAR analysis of their ovicidal activity against Tetranychus urticae'' [Bioorg. Med. Chem. Lett., 16, 4080-4084 (2006)]. Bioorg. Med. Chem. Lett., 16, 5473 (2006)

Kawakatsu M, Yamamoto Y and Miyagawa H.
Pyranonaphthoquinone pigment from cultured lichen mycobiont of Haematomma sp. Lichenology, 5(1), 31-36 (2006)

Suzuki J, Tanji I, Ohta Y, Toda K and Nakagawa Y.
QSAR of 2,4-diphenyl-1,3-oxazolines for ovicidal activity against the two-spotted spider mite Tetranychus urticae. J. Pestic. Sci., 31, 409-416 (2006)

Minakuchi C, Suzuki J, Toda K, Akamatsu M, Nakagawa Y.
Estimation of the hydrophobicity of 2,4-diphenyl-1,3-oxazoline analogs and QSAR analysis of their ovicidal activity against Tetranychus urticae. Bioorg. Med. Chem. Lett., 16, 4080-4084 (2006)

Yamamoto S, Watanabe B, Otsuki J, Nakagawa Y, Akamatsu M and Miyagawa H.
Synthesis of 26,27-bisnorcastasterone analogs and analysis of conformation-activity relationship for brassinolide-like activity. Bioorg. Med. Chem., 14, 1761-1770 (2006).

Wheelock C.E., Nakagawa Y, Harada T, Oikawa N, Akamatsu M, Smagghe G, Stefanou D, Iatrou K and Swevers L.
High throughput screening of ecdysone agonists using a reporter gene assay followed by 3-D QSAR analysis of the molting hormonal activity. Bioorg. Med. Chem., 14, 1143-1159 (2006)

Ishihara A, Asada Y, Takahashi Y, Yabe N, Komeda Y, Nishioka T, Miyagawa H and Wakasa K.
Metabolic changes in Arabidopsis thaliana expressing the feedback-resistant anthranilate synthase alpha subunit gene OASA1D. Phytochemistry, 67, 2349-2362 (2006)

Wakasa K, Hasegawa H, Nemoto H, Matsuda F, Miyazawa H, Tozawa Y, Morino K, Komatsu A, Yamada T, Terakawa T and Miyagawa H.
High-level tryptophan accumulation in seeds of transgenic rice and its limited effects on agronomic traits and seed metabolite profile. J. Exp. Bot., 57, 3069-78 (2006)

Ohnishi T, Nomura T, Watanabe B, Ohta D, Yokota T, Miyagawa H, Sakata K and Mizutani M.
Tomato cytochrome P450 CYP734A7 functions in brassinosteroid catabolism. Phytochemistry, 67, 1895-906 (2006)

Miyata K, Miyashita M, Nose R, Otake Y and Miyagawa H.
Development of a colorimetric assay for determining the amount of H2O2 generated in tobacco cells in response to elicitors and its application to study of the structure-activity relationship of flagellin-derived peptides. Biosci. Biotechnol. Biochem., 70, 2138-2144 (2006)

Original Articles

Matsuda F, Morino K, Ano R, Kuzawa M, Wakasa K and Miyagawa H.
Metabolic flux analysis of the phenylpropanoid pathway in elicitor-treated potato tuber tissue. Plant Cell Physiol., 46, 454-446 (2005)

Minakuchi C, Nakagawa Y, Kamimura M and Miyagawa H.
Measurement of receptor-binding activity of non-steroidal ecdysone agonists using in vitro expressed receptor proteins (EcR/USP complex) of Chilo suppressalis and Drosophila melanogaster In “New Discoveries in Agrochemicals.” (J. Marshall Clark, Hideo Ohkawa, Eds.). ACS Symp. Ser., 892, American Chemical Society, Washington, D.C., pp.191-200 (2005)

Miyashita M, Shimada T, Miyagawa H and Akamatsu M.
Surface plasmon resonance-based immunoassay for 17beta-estradiol and its application to the measurement of estrogen receptor-binding activity. Anal. Bioanal. Chem., 381, 667-73 (2005)

Morino K, Matsuda F, Miyazawa H, Sukegawa A, Miyagawa H and Wakasa K.
Metabolic profiling of tryptophan-overproducing rice calli that express a feedback-insensitive a subunit of anthranilate synthase. Plant Cell Physiol., 46, 514-521 (2005)

Nakagawa Y, Takahashi K, Kishikawa H, Ogura T, Minakuchi C and Miyagawa H.
Classical and three-dimensional QSAR for the inhibition of [3H]ponasterone A binding by diacylhydrazine-type ecdysone agonists to insect Sf-9 cells. Bioorg. Med. Chem., 13, 1333-1340 (2005)

Ogura T, Nakagawa Y, Minakuchi C and Miyagawa H.
QSAR for binding affinity of substituted dibenzoylhydrazines to intact Sf-9 cells. J. Pestic. Sci., 30, 1-6 (2005) Matsuda F, K. Morino, H. Miyazawa, M. Miyashita, and H. Miyagawa
Determination of Potato Glycoalkaloids using High-pressure Liquid Chromatography-Electrospray Ionizaion/Mass Spectrometry.
Phytochem. Anal. 15; 121-124, 2004

Minakuchi, C., Y. Nakagawa, Y. Soya and H. Miyagawa
Preparation of functional ecdysteroid receptor proteins (EcR and USP) using a wheat germ cell-free protein synthesis system.
J Pestic Sci 29; 189-194, 2004

Miyashita, M., T. Shimada, S. Nakagami, N. Kurihara; H. Miyagawa and Akamatsu, M
Enantioselective recognition of mono-demethylated methoxychlor metabolites by the estrogen receptor.
Chemosphere 54; 1273-1276, 2004

Nishiwaki, H., K. Sato, Y. Nakagawa, M. Miyashita, and H. Miyagawa
Metabolism of imidacloprid in houseflies.
J Pestic Sci 29; 110-116, 2004

Okazaki Y., T. Isobe, Y. Iwata, T. Matsukawa, F. Matsuda, H. Miyagawa, A. Ishihara, T. Nishioka and H. Iwamura
Metabolism of avenanthramide phytoalexins in oats.
Plant J 39; 560-572, 2004

Swevers, L., L. Kravariti, S. Ciolfi, M. Xenou-Kokoletsi, N. Ragoussis, G. Smagghe, Y. Nakagawa, B. Mazomenos, and I. Kostas
A cell-based high-throughput screening system for detecting ecdysteroid agonists and antagonists in plant extracts and libraries of synthetic compounds.
FASEB J 18; 134-136, 2004

Watanabe, B., S. Yamamoto, K. Sasaki, Y. Nakagawa, and H. Miyagawa
A simple synthesis of 6-deoxoteasterone and its 20-epimer.
Tetrahedron Lett 45; 2767-2769, 2004

Watanabe, B., Y. Nakagawa, T. Ogura and H. Miyagawa
Stereoselective synthesis of (22R)- and (22S)-castasterone/ponasterone A hybrid compounds and evaluation of their molting hormone activity. Steroids 69; 483-493, 2004

Uesusuki, S., B. Watanabe, S. Yamamoto, J. Otsuki, Y. Nakagawa and H. Miyagawa
Synthesis of Brassinosteroids of Varying Acyl Side Chains and Evaluation of Their Brassinolide-like Activity.
Biosci Biotech Biochem 68; 1097-1105, 2004

Kawakatsu, M., H. Miyagawa and N. Hamada
Variations in the concentrations of chemical substances produced by cultured lichen mycobionts.
Lichenology, 2 (1); 11-15, 2003

Kiriyama, K., H. Nishiwaki, Y. Nakagawa and K. Nishimura
Insecticidal activity and nicotinic acetylcholine receptor binding of dinotefuran and its analogues in the housefly, Musca domestica.
Pest Manag Sci, 59; 1093-1100, 2003

Matsuda, F., K. Morino, M. Miyashita and H. Miyagawa
Metabolic flux analysis of the phenylpropanoid pathway in wound-healing potato tuber tissue using stable isotope-labeled tracer and LC-MS spectroscopy.
Plant Cell Physiol, 44(5);, 510-517, 2003

Minakuchi, C., Y. Nakagawa, M. Kiuchi, A. Seino, S. Tomita and M. Kamimura
Molecular cloning and expression analysis of ultraspiracle (USP) from the rice stem borer Chilo suppressalis.
Insect Biochem Mol Biol, 33; 41-49, 2003

Minakuchi, C, Y. Nakagawa and H. Miyagawa
Validity analysis of a receptor binding assay for ecdysone agonists using cultured intact insect cells.
J Pestic Sci, 28, 51-53, 2003

Minakuchi, C., Y. Nakagawa, M. Kamimura and H. Miyagawa
Binding affinity of non-steroidal ecdysone agonists against the ecdysone receptor complex (EcR/USP) determines the strength of their molting hormonal activity.
Eur J Biochem, 270; 4095-4104, 2003

Miyashita, M., T. Nakamori, H. Miyagawa, M. Akamatsu, T. Ueno
Inhibitory activity of analogs of AM-Toxin, a host-specific phytotoxin from the Alternaria alternata apple pathotype, on photosynthetic O2 evolution in apple leaves.
Biosci Biotech Biochem, 67 (3); 635-638, 2003

Nishiwaki, H.,Y. Nakagawa, M. Kuwamura, K. Sato, M. Akamatsu, K. Matsuda, K. Komai, H. Miyagawa
Correlations of the electrophysiological activity of neonicotinoids with their binding and insecticidal activities.
Pest Manag Sci, 59; 1023-1030, 2003

Watanabe, B., Y. Nakagawa, and H. Miyagawa
Synthesis of a castasterone/ponasterone hybrid compound and evaluation of its molting hormone-like activity.
J Pestic Sci, 28; 188-193, 2003

Wheelock, C. E., Y. Nakagawa, M. Akamatsu and B. D. Hammock
Use of classical and 3-D QSAR to examine the hydration state of juvenile hormone esterase inhibitors.
Bioorg Med Chem, 11; 5101-5116, 2003

Ishihara, A., H. Miyagawa
Development of Agrochemicals in the Next Generation -new nanotechnologies in discovery and invention, H. Abe, et al., Editors.
Soft Science Inc.: Tokyo. p. 2-14, 2003

Miyashita, M.
Instrument for radiation measurement in life sciences (4). IV. Accelerator mass spectrometry in tracer studies ? Applications to biochemical studies-.
Radioisotopes, 52; 308-314, 2003

Nakagawa, Y., C. Minakuchi
Growth regulators: Insecticides in the Next Generation -new nanotechnologies in discovery and invention, H. Abe, et al., Editors.
Soft Science Inc.: Tokyo. pp.119-133, 2003

Nakagawa, Y.
Molting hormone in “Nougeikagaku no jiten,” A. Suzuki, S. Arai, Editors.
Asakura, pp168-171, 2003

Miyagawa, H., Y. Nakagawa, F. Malcolm, H. Inami, M. Suzuki
Main Topic 4-Formulation and application: Methodology, performance, safety.
J. Pestic. Sci. 28; 142-148, 2003

Miyashita, M, H. Nishiwaki
Topic A-3. Mode of Action.
J. Pestic. Sci. 28; 506-509, 2003

Wakasa, K., H. Miyagawa
Regulation of the metabolism in tryptophan biosynthetic process and its utilization.
Kagaku to Kogyo, 54; 494-499, 2003